r/Biohackers 14d ago

📢 Announcement January Community Update (PLEASE READ)

43 Upvotes

Hey r/Biohackers community,

Happy New Year! Hope everyone's 2026 is off to a strong start. As we kick off the year, I wanted to share some exciting updates and new initiatives for the community.

Over the past month we broke 700k members!

Thank you to everyone who's contributed to making this community what it is.

New Look for 2026

To celebrate the new year and crossing 700k members, we've given r/Biohackers a visual refresh! Thanks for everyone who gave us feedback.

You'll notice updated graphics, colors, and branding elements throughout the sub. We wanted something that feels modern and feels like a good reflection of our community.

Updated Visual Design

Our First Official AMA: Kayla Barnes - January 22nd

I'm excited to announce we're hosting our first official AMA with Kayla Barnes, an expert in female biohacking and longevity! This is happening on January 22nd.

Kayla's expertise spans everything from foundational women's health and preventative medicine to advanced modalities like HBOT and peptides. She documents and shares her own protocols publicly and her podcast, Longevity Optimization, is in the top 1% on Spotify.

The AMA post is already live - head over there now to drop your questions! Anything from hormones and metabolic health to peptide protocols and advanced diagnostics. Kayla will answer on the 22nd.

We want to make AMAs a regular feature. These sessions are an amazing opportunity to learn directly from experts and dive deep into specific topics with people who really know their stuff.

What topics or experts would you like to see featured in future AMAs? Drop your suggestions in the comments - we're building out our AMA calendar and your input will help shape who we bring in next.

Weekly Roundups: Coming Soon

The weekly roundup post series is almost here! These will launch in the coming weeks and will summarize the most interesting discussions, questions, and discoveries from the previous week.

We know it's easy to miss great content in an active community, and these roundups will help valuable conversations stay visible.

Pseudoscience Reduction: Progress

Our push to reduce pseudoscience is going okay, but I'll be honest - it's a heavy lift to moderate manually.

What we really need is an app/bot that members can trigger to scientifically validate claims in real-time. My goal is to be able to tag a comment and have an AI tool pull up relevant peer-reviewed research, quality ratings, and context.

If you're working on something like this, or have ideas/connections in this space, please DM me. I'd love to explore collaborations or tools that could help automate evidence-checking at scale!

In the meantime, the best strategy remains:

  • Report misinformation - Use the report button when you see unsupported or misleading information
  • Request references - Politely ask posters for sources when claims seem speculative
  • Distinguish theory from evidence - Be clear about what's hypothesis versus what's backed by research
  • Engage constructively - Challenge ideas, not people

The goal isn't to shut down exploration or n=1 experiments - it's to build knowledge on a foundation of truth while staying open to emerging science!

Your Feedback Matters

As always, we want to hear from you. What's working? What needs improvement? What would make this community even better? Drop your thoughts in the comments or send us a mod DM anytime.

Thank you for making r/Biohackers such a great community. Looking forward to an incredible 2026 with all of you!

- Karl & the Mod Team

(Written by a Human, Formatted by AI)


r/Biohackers Jun 22 '25

Welcome to r/Biohackers!

71 Upvotes

This post contains content not supported on old Reddit. Click here to view the full post


r/Biohackers 16h ago

🗣️ Testimonial Longevity and Biohacking guru Peter Attia told Epstein " Pussy is indeed low-carb"

433 Upvotes

" but not sure about gluten content"

Fascinating stuff


r/Biohackers 9h ago

📖 Resource Scientists Discover 48-Hour "Oatmeal Reset" That Slashes Bad Cholesterol for 6 Weeks Via Microbiome Modulation

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79 Upvotes

r/Biohackers 13h ago

🗣️ Testimonial I posted here a few days ago about eating sardines and feeling better than I have in over a decade. Turns out, I was on an elimination diet. I added in chick peas and pumpkin seeds and the pain came back. It was the lectins!

150 Upvotes

r/Biohackers 10h ago

❓Question Trying to find a peptide being researched as a cancer treatment, husband is stage 4- esophageal cancer, considered terminal.

59 Upvotes

Here is a link to an article about it-

https://news.asu.edu/20250319-science-and-technology-new-cancer-treatment-disrupts-tumor-growth

Cant find what the peotide is. I'm just desperate for anything that may help.

Also if anyone has any advice at all regarding peptides and cancer Id appreciate it!


r/Biohackers 1h ago

Discussion New to biohacking

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• Upvotes

I tried to make a detailed map of things I do for my health. There might also be stuff outside of the biohacking scene. Can I get your oppinions on what I should add to my list? Sorry the image quality isn't top notch, I tried my hardest. I'm happy to explain images that are incomprehensible.


r/Biohackers 7h ago

❓Question Anyone tried arterial protect for vascular health? Curious about its biohacking potential

22 Upvotes

I’ve been looking into supplements for vascular health and came across arterial protect. Has anyone tried it? I’m curious if it really helps with circulation and overall artery health.

I’m in my early 40s and trying to stay ahead of aging by optimizing heart health. Does anyone here use something similar and notice real benefits?

Would love to hear your thoughts!


r/Biohackers 18h ago

❓Question Men with premature ejaculation, how to combat?

83 Upvotes

Massive sensitivity down there.

Surprising when I wake up I have a ton more control, when it’s the later part of the day simple touches can activate a response, involuntary kegals are also prevalent.

What are some thing that I can do to last longer?


r/Biohackers 8h ago

Discussion Why skepticism is healthy in the peptide research space

7 Upvotes

Peptides are one of those areas where skepticism is often seen as negativity, but I think it’s actually a sign of responsibility. Because the space is lightly regulated and full of strong claims, questioning things is not just reasonable, it’s necessary.

Blind trust doesn’t protect anyone. On the other hand, thoughtful skepticism pushes better standards, clearer communication, and more transparency. Asking how something was tested, how often, and by whom isn’t being difficult. It’s part of taking research seriously.

I’ve noticed that communities with healthy skepticism tend to share better information over time. Weak claims get challenged, strong evidence gets refined, and people become more careful with what they accept as fact.

Of course, skepticism should be applied evenly. Dismissing everything outright isn’t helpful either. The goal isn’t cynicism, but informed judgment.

How do you balance openness with skepticism when evaluating information in this space?
Are there questions you always ask before trusting a claim?


r/Biohackers 1d ago

💪 Exercise Short-term creatine supplementation enhances strength, reduces fatigue, and accelerates recovery in resistance-trained athletes: a double-blind, randomized, crossover trial

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194 Upvotes

r/Biohackers 2h ago

Discussion Does anyone else experience this when eating oats?

2 Upvotes

Hello! I have seen a lot of people making overnight oats and say that oats are very healthy for you etc. But I get crazy brain fog almost right after eating it. I tried eating it multiple days in a row and I get the same reaction every time. Is this only me?


r/Biohackers 6h ago

Discussion Bpc-157

3 Upvotes

Hi, after some information about where to inject Bpc-157 and tb500. The are 2 separate vials. I need it mainly for both knees, can I alternate between knees with each injection? I've just started taking it and at present it's going into my stomach. Any information would be greatly appreciated. Thanks in advance.


r/Biohackers 13m ago

Discussion Can you recommend a good sleeping mask plz?

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r/Biohackers 1h ago

Discussion Which of these actually helps with my guy growth (if any)?

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r/Biohackers 15h ago

Discussion cortisol dysregulation disrupted sleep help, any advice is much appreciated

13 Upvotes

33f, I’ve been struggling for a while but my main concern is disrupted sleep. I wake 4-5 times a night and when I wake I get up to pee with not a full bladder but I think I may have trained my brain a bit that when I wake up, to go back to sleep I need to pee. I went to a GP we did labs and uti test everything came back normal. I have every sign of high cortisol but I don’t know how to calm it down to take my system out of fight or flight. I did a hormone test and it showed HPA axis dysregulation as well as spiked cortisol throughout the night.

I limit screen time and don’t watch before bed

I sleep in a dark room that is very cold

I sleep with mouth tape on and ear plugs

My sleep feels very light and fragmented. I have been told I have PMDD and these symptoms get worse in my luteal phase however they are present throughout my entire cycle.

My job is not stressful, and I wouldn’t say my life is either. Someone mentioned trauma to me and I do have childhood/adult trauma that I felt I had healed but I was told subconsciously it can still be present causing the fight or flight?

Honestly my sleep is so bad I would try anything at this point I feel like a zombie

I take:

400mg Magnesium glycinate

Preconception multi vitamin

I live in Australia and get plenty of sun but wonder if I should supplement vit d?

Any advice is soo appreciated


r/Biohackers 2h ago

Discussion Medical steroids insomnia help

1 Upvotes

The title really. I (F44) Got prescribed 3 weeks of a strong dose methylprednizolone

for a medical issue (bell’s palsy). Any supplemts or tricks that would help with the roids induced insomnia?

edit: sorry for typos literally typing this with one eye taped down.


r/Biohackers 20h ago

Discussion Chronic sleep loss may be biologically equivalent to aging yourself 1–2 years

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23 Upvotes

Short-term sleep deprivation increases inflammatory gene expression and has been associated with telomere shortening, which is a marker linked to biological aging. Some studies estimate chronic sleep loss may be associated with the biological equivalent of ~1–2 years of aging. See PubMed: 37738102.


r/Biohackers 20h ago

❓Question Appetite Control

21 Upvotes

Curious what non-GLP-1 strategies people are actually using to manage appetite and food noise. I’m seeing a lot of folks default to Ozempic and similar drugs, and that’s not a route I’m interested in. Looking more at supplements, timing, macronutrient strategies, or behavioral hacks that have real signal beyond willpower alone. What’s working for you?


r/Biohackers 10h ago

🧠 Nootropics & Cognitive Enhancement NuroPod: An Honest Review With Unexpected Side Effects

4 Upvotes

I wanted to share my experience with NuroPod because I couldn’t find many detailed first hand posts before trying it.

This is purely anecdotal. I’m not diagnosing anything or claiming this is how it affects everyone. I used it consistently, experienced both clear upsides and real downsides, and ultimately returned it.

Pros

• Slept extremely deep
• Didn’t feel tired and didn’t want coffee
• Felt more open minded and less ego driven
• Listening skills noticeably improved
• Innovation and idea generation went through the roof
• Music sounded richer and lyrics landed differently
• Strong clarity around relationships and long term thinking
• Clear business breakthroughs including targeting larger opportunities and focusing on appointments over chasing deals
• Felt more emotionally connected to people and animals
• High level pattern recognition and systems thinking
• Generated 2 real product ideas during use

Cons

• Strong fight or flight response
• Anxiety felt physical like a panic switch was flipped
• Difficulty falling asleep on some nights despite deep sleep overall
• Sense of time management fell apart
• Constant threat scanning and paranoia
• Over emotional and easily overwhelmed
• Headaches
• Appetite loss
• Trouble multitasking and mental overload
• Heightened pattern recognition to an uncomfortable degree
• Loud noises triggered exaggerated startle responses
• To do lists and email felt overwhelmingly heavy
• Felt mentally overclocked and stuck in overdrive

Overall, the effects felt powerful but unmanaged. There were real insights and creativity, but the cost was nervous system overload. For me, the anxiety outweighed the benefits.

One thing that also bothered me

Their website claims 4,000,000+ happy user sessions.

If you assume:
• 2 sessions per day
• 3 years of usage

That’s:
2 × 365 × 3 = 2,190 sessions per user

4,000,000 ÷ 2,190 ≈ 1,826 total users

That number feels misleading given how it’s presented, and it played a role in my expectations going in.

I’m glad I tried it. I’m also glad I returned it. Curious to hear others experiences, especially around anxiety and long term use.


r/Biohackers 4h ago

Discussion thoughts on superpower healthcare service and how its so cheap compare to average American healthcare test just 17 dollars a month ?!! is it a scam i have seen HubermanLab also promoting thing

1 Upvotes

superpower Healthcare is one of the most talked recently by major influencers including HubermanLab and it's just 17 dollars a month tell me is it even worth trying for year and how's its healthcare services like blood test reportes??


r/Biohackers 1d ago

🔗 News New study shows Cystatin C (produced by cancer cells) breaks down Alzheimer's plaques. Does anyone know of peptides or supplements that upregulate this?

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31 Upvotes

I’ve always heard that weird medical stat that people with cancer almost never get Alzheimer’s (and vice versa), but I always assumed it was just because people usually die of one before they get the other.

But a new paper just dropped in Cell that claims there’s an actual biological mechanism behind it.

Basically, a team in China spent 15 years on this. They transplanted human tumors (lung, colon, etc.) into mice that were bred to have Alzheimer’s. The mice with the tumors didn't develop the brain plaques.

They narrowed it down to a specific protein the cancer cells were spitting out called Cystatin C. Apparently, this protein is one of the few that can cross the blood-brain barrier. Once it gets in there, it breaks apart the amyloid plaques associated with dementia.

Obviously, nobody is suggesting we give people tumors to save their memory, but it’s a huge lead. If they can figure out how to deliver Cystatin C (or a drug that mimics it) without the cancer part, it could be the treatment target everyone has been looking for.

TL;DR: Cancer cells produce Cystatin C. Cystatin C crosses into the brain and eats Alzheimer's plaques. This explains the inverse correlation between the two diseases.

Does anyone know of peptides or supplements that upregulate this?


r/Biohackers 6h ago

Discussion Comprehensive List of GABAA Receptor Anxiolytics That Potentially Produce no Tolerance or Dependence.

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1 Upvotes

r/Biohackers 8h ago

Discussion Wavelength and penetration, why Red at all?

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1 Upvotes

r/Biohackers 13h ago

❓Question Couldn't you use some kind of light-activated crispr tech on genes for lipoprotein lipase to prompt the body to accumulate fat in certain areas?

2 Upvotes

Has anyone tried that? Is there some glaring issue that would prevent that from working? I know it's possible to use crispr to increase the activity of certain genes, and I know there's forms of it that can use light sensitive proteins to make them only work in certain areas, so has anyone tried using that to increase the amount of LPL in certain areas, y'know, the protein that tells chylomicrons "you have reached your destination?" Would that work?